Importation of KPC-2-producing Escherichia coli from India

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Importation of KPC-2-producing Escherichia coli from India.

Sir, The production of carbapenem-hydrolysing b-lactamases is increasingly reported in Enterobacteriaceae. Among the different types of carbapenemases, the emergence of the Ambler class A KPC-type b-lactamases is of great concern, since those enzymes hydrolyse all b-lactams with the exception of cephamycins. Enterobacterial isolates producing KPC-type b-lactamases were reported in many areas in...

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Environmental KPC-producing Escherichia coli isolates in Portugal.

Carbapenemase-producing isolates of the Enterobacteriaceae are reported increasingly worldwide (9). Besides the emergence of OXA-48 and NDM-1 producers in specific geographical areas, KPC-producing isolates are endemic in many places (8). Those KPCs hydrolyze all -lactams, including carbapenems at a significant level, with the exception of cephamycins. The blaKPClike genes have been reported mo...

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Emergence of Escherichia coli sequence type 131 isolates producing KPC-2 carbapenemase in China.

Twenty-two KPC-2-producing Escherichia coli isolates were obtained from three hospitals in Hangzhou, China, from 2007 to 2011. One isolate, with OmpC porin deficiency, exhibited high-level carbapenem resistance. Pulsed-field gel electrophoresis showed that few isolates were indistinguishable or closely related. Multilocus sequence typing indicated that sequence type 131 (ST131) was the predomin...

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Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv Medical Center, 2005 to 2008.

All of the carbapenem-resistant Escherichia coli (CREC) isolates identified in our hospital from 2005 to 2008 (n = 10) were studied. CREC isolates were multidrug resistant, all carried bla(KPC-2), and six of them were also extended-spectrum beta-lactamase producers. Pulsed-field gel electrophoresis indicated six genetic clones; within the same clone, similar transferable bla(KPC-2)-containing p...

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ژورنال

عنوان ژورنال: Journal of Antimicrobial Chemotherapy

سال: 2011

ISSN: 0305-7453,1460-2091

DOI: 10.1093/jac/dkr426